Amisulpride
Generic Name:
Amisulpride
Brand Names:
Solian (Australia)
Amisulpride Description:
Amisulpride is an antipsychotic agent used in the treatment of schizophrenia. While the exact cause of schizophrenia is unknown, experts believe the condition may be the result of abnormal activity in the brain. Amisulpride acts on the central nervous system to help reduce this activity.
Amisulpride Side Effects:
The most common side effects of amisulpride include:
- Drowsiness
- Weight gain
- Dizziness
- Increased appetite
- Constipation
- Dry mouth
- Insomnia
- Anxiety
- Agitation
For more information, see our amisulpride side effects page.
Amisulpride Uses:
Amisulpride is used in the treatment of schizophrenia, a chronic psychotic disorder characterized by symptoms such as delusions, hallucinations, paranoia, emotional unresponsiveness and social withdrawal.
Amisulpride Interactions:
Amisulpride should not be used in conjunction with the following medications:
- Quinidine
- Disopyramide
- Amiodarone
- Sotalol
- Cisapride
- Antibiotics such as erythromycin and pentamidine
- Levodopa
- Thioridazone
- Methadone
Amisulpride may also interact with the following medications:
- Diltiazem
- Verapamil
- Clonidine
- Digoxin
- Beta blockers
- Amphotericin B
- Thioridazine
- Chlorpromazine
- Trifluperazine
- Pimozide
- Haloperidol
- Imipramine
- Lithium
- Diuretics
- Stimulant laxatives
- Glucocorticosteroids
- Tetracosactides
- Anxiolytics or sedatives
- Antihistamines
- Medications for high blood pressure
- Central nervous system depressants
Amisulpride may interact with other medications or substances that are not listed above. In order to prevent potential complications, patients should talk with their doctor about the use of any other medicines, vitamins or supplements before beginning treatment with amisulpride.
Amisulpride Dosage Information:
Typical Dosage Recommendations
Amisulpride dosages may vary among patients. Your doctor will establish the size and frequency of your dosage according to your individual needs. Patients should follow the dosage guidelines set by their doctor.
Amisulpride is administered in the form of an oral tablet and an oral solution. Patients generally take a daily dosage between 50 and 800 mg. In some cases, patients may take 1,200 mg a day.
Missing a Dose of Amisulpride
If you forget to take a dose of amisulpride, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your normal dosage schedule. Do not consume a double dose of amisulpride to compensate for a missed dose.
Amisulpride Overdose
The most common symptoms of an amisulpride overdose include:
- Drowsiness
- Slurred speech
Patients should seek immediate medical attention if they have taken too much of this medication.
Amisulpride FDA Approval:
Amisulpride has not yet been approved by the FDA for sale in the United States. The medication is available in other countries such as Australia.
Amisulpride Recall/Black Box Warning Information:
Amisulpride does not carry any black box warnings.
Other Warnings
Patients undergoing treatment with amisulpride may be at risk of developing the following serious conditions:
- Tardive dyskinesia – Tardive dyskinesia is a potentially irreversible condition characterized by involuntary, dyskinetic body movements. Elderly patients, especially elderly women, may be more susceptible to tardive dyskinesia than others. The risk of tardive dyskinesia increases with higher doses and extended use of antipsychotic medications.
- Neuroleptic malignant syndrome (NMS) – NMS is a serious and potentially fatal condition. Common symptoms of NMS include fever, rigid muscles and altered mental state, among others.
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