Avandamet
Generic Name:
Metformin, Rosiglitazone
Brand Names:
Avandamet
Avandamet Description:
Avandamet is used in the treatment of patients with type 2 diabetes. The medication treats high levels of blood sugar by helping the body utilize insulin, a hormone that affects metabolism, more effectively, improving the control of blood sugar. Avandamet also helps the liver create less sugar.
Avandamet is not approved for the treatment of patients with type 1 diabetes or diabetic ketoacidosis.
Avandamet Side Effects:
Serious side effects associated with Avandamet use include:
- Weight gain
- Liver problems
- Diabetic eye disease (Macular edema)
- Fractures
- Low red blood cell count
- Low blood sugar
- Ovulation
For more information, see our Avandamet side effects page.
Avandamet Uses:
Patients take Avandamet to treat type 2 diabetes, a condition that occurs when the body does not produce enough insulin, or the cells in the body ignore the presence of insulin. Insulin is instrumental to the body as it helps regulate sugar in the bloodstream. Type 2 diabetes is the most common form of the chronic disease.
Avandamet Interactions:
Inform your doctor of the use of any medications, vitamins, or supplements prior to beginning Avandamet treatment.
Alert your doctor if you are taking any of the following medicines, as special recommendations may be made concerning these medications:
- Insulin
- Nitrate medicines
- High blood pressure medications
- High cholesterol medications
- Heart failure medications
- Heart disease or stroke prevention medications
Avandamet Dosage Information:
Typical Dosage Recommendations
Patients should take Avandamet exactly as prescribed by a doctor. Take Avandamet orally with meals.
Patients may be prescribed Avandamet along with other diabetes medications. Follow your doctor’s dosing recommendations for all medications.
Missing a Dose of Avandamet
If a dose of Avandamet is missed, take the missed dose as soon as you remember. If it is nearly time for your next dose, skip the missed dose and take the next dose to resume your normal dosing schedule. Do not take multiple doses of Avandamet.
Avandamet Overdose
If an Avandamet overdose occurs, seek immediate medical attention.
Avandamet FDA Approval:
October 10, 2002
Avandamet Recall/Black Box Warning Information:
Avandamet carries a Black Box warning for the following conditions:
- Congestive heart failure
- Myocardial ischemia (heart condition caused by lack of blood flow to the heart)
- Lactic acidosis (buildup of lactic acid in the blood)
In April 2005, Avandamet was recalled following a manufacturing defect that may have resulted in tablets splitting apart, causing patients not to receive the proper amount of the medication.
In July 2008, Avandamet was recalled following an incorrect packaging insert. The insert did not contain the most current prescribing information.
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