Boniva Injection Side Effects
Boniva injection may cause the following side effects, and you should contact your doctor if any symptoms increase in severity or do not improve:
- Heartburn
- Diarrhea
- Pain in the extremities (arms, legs)
- Upset stomach
- Flu-like symptoms
Contact your doctor immediately if you experience any of the following more severe side effects:
- Pain or trouble swallowing
- Chest pain
- Heartburn that does not get better
- Allergic reaction symptoms such as skin rash, hives, wheezing, or swelling of the face, lips, tongue, or throat
- Bone, joint, or muscle pain
- Numbness of heaviness in the jaw
- Poor healing of the jaw
Specific precautions
Bone death (osteonecrosis) can occur in patients receiving treatment with Boniva injections. If you experience jaw pain, notify your doctor immediately. Consult with your doctor before having any dental surgery.
You may experience bone, joint or muscle pain after receiving Boniva injections. Pain usually subsides after treatment has stopped.
Rarely, treatment with bisphosphonates can cause kidney toxicity and even kidney failure. Tell your doctor about any history of kidney impairment.
Conditions or medications that may be affected by the drug or interact negatively with the drug
There are a number of conditions that may be affected by the Boniva injection, including:
- Anemia
- Blood clotting problems
- Cancer or cancer treatment
- Dental or oral disease or infection
- Family history of osteoporosis or other bone problems
- Previous broken bone
- Smoking
- Thin body frame
- Low calcium levels in the blood (hypocalcemia)
- Kidney problems
Low calcium levels in the blood (hypocalcemia) must be treated before beginning Boniva injections.
Kidney problems including kidney failure may be made worse when taking Boniva.
Dental or oral infections may be worsened by Boniva and may lead to osteonecrosis.
Safety has not been established in patients who are pregnant. Since Boniva is typically used for post-menopausal women, this may not be an issue. Talk to your doctor if are pregnant or plan to become pregnant.
Safety and effectiveness of Boniva has not been established in children.
Questions to ask your physician
Inform your doctor if you are on a low-sugar or low-sodium diet. Your doctor may recommend that you eat a diet balanced in vitamin D and calcium, and you will need to take calcium and vitamin D supplements.
Tell your doctor if you have ever had any kind of allergic reaction to the ingredients in Boniva.
Additional drugs
Consult your doctor about any medications, prescription, supplements, or herbs that you will be or may be taking in addition to Boniva. This information must be disclosed in order to prevent the possibility of drug interactions.
Food/alcohol
There are no food restrictions unless your doctor orders a special diet with Boniva, including calcium and Vitamin D supplements.
Certain activities
Boniva should be avoided in pregnancy. Boniva falls under the FDA class C category for pregnancy. However, it is possible for Boniva to be used if the benefits outweigh the risks.
Boniva should be avoided while breastfeeding unless clearly needed.
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September 7, 2010, 9:59 am
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September 2, 2010, 12:51 pm
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September 1, 2010, 3:16 pm
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August 31, 2010, 2:01 pm


