Copegus
Ribavirin
Copegus, Rebetol, Ribasphere, Virazole
Copegus is an antiviral medication that belongs to a class of drugs known as nucleoside analogues. Copegus is used in conjunction with other medications to treat patients with chronic hepatitis C, an infection that affects the liver.
The most common side effects of Copegus include:
- Fatigue
- Nausea
- Loss of appetite
- Rash and itching
- Cough
For more information, see our Copegus side effects page.
Copegus is used in conjunction with another medication known as peginterferon alfa-2a (Pegasys) to treat adults with chronic hepatitis C and compensated liver disease. Chronic hepatitis C is a viral infection that can lead to serious complications over time if left untreated.
Hepatitis C infections are contracted through exposure to contaminated blood. Infections are most commonly acquired due to needle sharing during the use of illegal drugs.
Copegus may interact with the following medications:
- Azathioprine (Imuran)
- Anti-HIV medications
Copegus may interact with other medications or substances that are not listed above. In order to avoid potentially hazardous interactions, patients should talk with their doctor about the use of any other medicines, vitamins or supplements before beginning treatment with Copegus.
Typical Dosage Recommendations
Copegus dosages may vary among patients. Your doctor will determine the size of your dosage according to your individual body weight. Patients should follow the dosage guidelines set by their doctor.
Copegus is administered in the form of an oral tablet. Patients usually take the medication once in the morning and once in the evening. Patients should take Copegus tablets with food.
Missing a Dose of Copegus
If you forget to take a dose of Copegus but remember that same day, take the missed dose immediately. Then take your next dose as scheduled. If you do not remember that same day, contact your doctor for instructions. Do not consume a double dose of Copegus to compensate for a missed dose.
Copegus Overdose
An overdose of Copegus may result in low calcium and magnesium levels. Patients should seek immediate medical attention if they believe they have taken too much of this medication.
December 3, 2002
Copegus carries a black box warning informing consumers and health care professionals of the following:
- Copegus is not an effective treatment when used alone. The medication has only been proven safe and effective when used in combination with other medications such as peginterferon alfa-2a.
- Copegus may cause a worsening of heart disease, as well as heart attacks. Patients with a history of severe heart disease should not take Copegus.
- Copegus has been associated with birth defects. Consequently, both men and women must use effective contraceptive measures while undergoing treatment with the medication and during the six-month period directly following the end of treatment.
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