Endocet
Generic Name:
Oxycodone and acetaminophen
Brand Names:
Endocet, Oxycet, Percocet, Roxicet, Roxicet 5/500, Roxilox, Tylox, Tylox-365
Endocet Description:
Endocet is a combination oxycodone and acetaminophen medication prescribed to relieve moderate to severe pain, with or without fever. Endocet is considered a narcotic pain reliever, with properties similar to codeine.
Endocet Uses:
Endocet is used to relieve a wide variety of pain, including chronic pain, headaches, migraines, backaches, toothaches, and joint or muscular pain. Endocet works on the pain receptors of the body to change the way they sense pain and to cool the body temperature if a fever is present.
The ingredient oxycodone is a semi-synthetic opioid that acts on the central nervous system, providing pain relief. Other effects include anxiety relief, euphoria, and relaxation.
Narcotic analgesics such as Endocet are useful in relieving pain with smaller doses than normal analgesics. However, drug dependency with Endocet can occur, and patients may require greater quantities.
The acetaminophen in Endocet helps reduce the likelihood of dependency on the drug by limiting the maximum daily dosage.
Endocet Interactions:
The following central nervous system depressant medications may interact with Endocet:
- Antihistamines or medicine for hay fever, allergies, or colds
- Sedatives, tranquilizers, or sleeping medicines
- Other prescription pain medicines or narcotics
- Barbiturates
- Seizure medication
- Muscle relaxants
- Anesthetics
The following medications include acetaminophen and increase the chance of unwanted side effects:
- Aspirin or other salicylates
- Diclofenac (Voltaren)
- Diflunisal (Dolobid)
- Etodolac (Lodine)
- Fenoprofen (Nalfon)
- Floctafenine (Idarac)
- Flurbiprofen, oral (Ansaid)
- Ibuprofen (Motrin)
- Indomethacin (Indocin)
- Ketoprofen (Orudis)
- Ketorolac (Toradol)
- Meclofenamate (Meclomen)
- Mefenamic acid (Ponstel)
- Nabumetone (Relafen)
- Oxaprozin (Daypro)
- Phenylbutazone (Butazolidin)
- Piroxicam (Feldene)
- Sulindac (Clinoril)
- Tenoxicam (Mobiflex)
- Tiaprofenic acid (Surgam)
- Tolmetin (Tolectin)
Endocet Dosage Information:
Typical Dosage Recommendation:
Dosages of Endocet depend on the condition being treated and the patient’s response to the medication. Endocet is available in multiple strengths, including:
- 5 mg oxycodone/ 325 mg acetaminophen (maximum of 12 tablets daily)
- 7.5 mg oxycodone/325 mg acetaminophen (maximum of 8 tablets daily)
- 7.5 mg oxycodone/500 mg acetaminophen (maximum of 8 tablets daily)
- 10 mg oxycodone/325 mg acetaminophen (maximum of 6 tablets daily)
- 10 mg oxycodone/650 mg acetaminophen (maximum of 6 tablets daily)
Adults are generally prescribed one tablet every six hours, as needed for pain relief. The total daily dose of acetaminophen should not exceed 4000 mg.
Patients who have been treated with Endocet for more than a few weeks and who no longer require therapy should gradually reduce their daily dosage in order to avoid withdrawal symptoms.
Missing a Dose:
If a dose of Endocet is missed, take the missed dose as soon as possible. If it is almost time for the next scheduled dose, skip the missed dose and wait to return to your regular dosing schedule. Do not double dose on this medication.
Overdosing:
Overdose is one of the primary abuses of narcotic analgesics such as Endocet. Patients must check the labels of all over-the-counter cough syrups and analgesics to check whether they contain acetaminophen, as additional acetaminophen may lead to a dangerous overdose. A large quantity of acetaminophen can cause liver damage. Seek emergency medical attention if you suspect an overdose. Overdose of narcotic analgesics like Endocet may result in the following symptoms:
- Confusion
- Excessive sleepiness
- Heart rhythm changes
- Vomiting
- Nausea
- Shallow breathing
- Loss of appetite
- Sweating
- Pain in the upper right part of the stomach
Endocet FDA Approval:
August 31, 1976
Endocet Recall/Black Box Warning Information:
There are no recalls or Black Box warnings on Endocet.
Other Warnings
Endocet must only be taken at the prescribed amount and at prescribed intervals to avoid addiction.
Endocet is a Schedule II controlled substance, with properties similar to codeine and morphine. The potential for abuse or addiction exists.
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September 7, 2010, 9:59 am
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September 2, 2010, 12:51 pm
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September 1, 2010, 3:16 pm
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August 31, 2010, 2:01 pm
