Gardasil
Human papillomavirus vaccine
Gardasil
Gardasil is a new vaccine designed to protect girls and young women against the human papillomavirus (HPV). It is approved for use by females between 11 and 26 years old and protects against the kind of cervical cancer that is caused by some types of HPV. It can also protect against vaginal and vulvar cancer and genital warts, but cannot protect against every kind of cancer that can be contracted in those areas. Gardasil does not protect against other kinds of cervical cancer or any other kinds of cancers, and should not be used to participate in careless sexual behavior. Gardasil will not treat an already-existing HPV infection or genital warts.
The most common condition that Gardasil is approved for the prevention of certain strands of the human papillomavirus, a sexually transmitted disease. HPV often does not have many symptoms so many women who contract the disease are often unaware that they have it and, therefore, do not get it treated. If left untreated, the human papillomavirus can cause cervical cancer and other conditions such as genital warts, and may lead to infertility. A person who contracts cervical cancer from the human papillomavirus cannot have the cancer treated by Gardasil and Gardasil is not a treatment for any kind of cancer. Instead, it is a vaccine designed to prevent certain strands of a sexually transmitted disease that may potentially lead to cervical cancer in the future.
The disease can also lead to cancers of the vulva or the vagina. Vaginal and vulvar cancers are very significant and can be very serious. The Gardasil vaccine can help to protect women from specific types of these cancers and is worth consideration for women in the approved age group, especially if they are or plan to be sexually active. Many women and young girls are uncomfortable talking to their doctors about their sexual activity, especially if they have had or are interested in having multiple partners, but sexual activity places women at higher risk for HPV and other sexually transmitted diseases, making it important to keep open and honest communication with a doctor when addressing sexual activity.
Certain medications may interact with the Gardasil vaccine and influence the drug’s effectiveness. Drugs that may interact with Gardasil include:
- Alkylating agents (cyclophosphamide)
- Antimetabolites (fluorouracil, methotrexate)
- Corticosteroids (prednisone)
- Cytotoxics (cisplatin).
This is not a comprehensive list of drugs that may interact with Gardasil and it is wise to inform a doctor of the use of any medication before receiving the Gardasil vaccine.
Typical Dosage Recommendation:
Gardasil is given by injection in a doctor's office. The vaccine includes a series of three shots, and it is given in either the upper arm or the thigh. One shot is given, followed by a booster shot two months later and the third shot six months after that. Not receiving all three shots may not protect a patient against the disease. Any other vaccines, including a flu shot, should not be given until a patient has received all three Gardasil shots. Before receiving the Gardasil vaccine, inform a doctor of any of the following issues:
- high fever or signs of infection
- bleeding or blood clotting disorder
- weak immune system
- blood thinner taken as a prescription, such as warfarin
Missing a Dose:
Should a patient miss an appointment for a scheduled injection or fall behind schedule in the suggested time frame recommended for Gardasil injections, the patient should receive the next dose of the medication as soon as possible. A patient will not need to start over with the first injection and should receive all three injections to ensure complete protection against certain strands of HPV.
Overdosing:
Since Gardasil injections are administered by a doctor and are scheduled at the doctor’s office, an overdose of the vaccine is highly unlikely.
June 15, 2006
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