Heparin
Heparin
Hep-Lock, Hep-Pak CVC, Heparin Lock Flush
Heparin is an anticoagulant and blood thinner, designed to prevent blood clots from forming. The medication is used for clots in the arteries, veins, or lungs and has been used before surgery in some people to help reduce their risk of blood clots. There are other purposes for which Heparin is used, though additional uses are not common.
Heparin is designed specifically to treat blood clots in the veins, arteries and lungs. While Heparin has been used for other purposes, addressing blood clots is the most common use for the medication. Some people who use Heparin find that they bleed too much, though this can be corrected by adjusting the dosage. Others find the side effects of Heparin too difficult to handle and are given another type of blood thinning medication instead. For most people who need a strong anticoagulant, Heparin works well and does not cause serious problems. The blood clots that can be seen when Heparin is not used are generally much more serious than most of the problems that may appear in some cases after using Heparin.
Not all blood clots respond well to other anticoagulant drugs, which is why some people need to take Heparin, especially if they have frequent problems with blood clots or if they have used other similar medications without success. Sometimes Heparin is used originally and after a while an oral anticoagulant medication is taken, during which time the patient slowly stops use of Heparin. Ceasing use of medications like Heparin too quickly can cause blood clots to form, so extreme care must be taken when changing or withdrawing from medications like Heparin. Blood clots can cause death, and can also lead to embolisms, heart attacks and strokes, so it is very important that any potential blood clots be treated quickly. Those who are at risk for blood clots should be evaluated.
Notify a doctor if aspirin or other NSAIDs (non-steroidal anti-inflammatory drugs) such as the following are used:
- Ibuprofen (Motrin, Advil)
- Naproxen (Aleve, Naprosyn)
- Diclofenac (Voltaren)
- Diflunisal (Dolobid)
- Etodolac (Lodine)
- Flurbiprofen (Ansaid)
- Indomethacin (Indocin)
- Ketoprofen (Orudis)
- Ketorolac (Toradol)
- Mefenamic acid (Ponstel)
- Meloxicam (Mobic)
- Nabumetone (Relafen)
- Piroxicam (Feldene)
Other drugs that can affect Heparin include:
- Other blood thinners, such as warfarin (Coumadin)
- Salicylates such as aspirin, Disalcid, Doan's Pills, Dolobid, Salflex, Tricosal, and others
- Dipyridamole (Persantine)
- Nicotine cigarettes, gum, lozenges, or skin patches
- Cold, allergy, or sleep medications (Allerest, Benadryl, Chlor-Trimeton, Dimetapp, Sominex, and others)
- Hydroxychloroquine (Plaquenil, Quineprox)
- Digoxin (digitalis, Lanoxin, Lanoxicaps)
- Demeclocycline (Declomycin)
- Doxycycline (Adoxa, Doryx, Oracea, Vibramycin)
- Minocycline (Dynacin, Minocin, Solodyn, Vectrin)
- Tetracycline (Brodspec, Panmycin, Sumycin, Tetracap)
Typical Dosing Recommendation:
Heparin is administered through an injection into the skin or via a needle into a vein. The medication should not be injected into the muscle and should not be done by a patient without full understanding as to how to administer Heparin. The disposable needled used to inject Heparin should be used one time and then properly discarded. The injection should not be administered if the color of the medication has changed or if particles are present in the drug.
Missing a Dose:
If a dose of Heparin is missed, a doctor should be notified to recommend the best option based on the patient’s individual situation and dosage.
Overdosing:
An overdose of Heparin is a serious issue and immediate medical attention should be sought. Symptoms of an overdose include bloody urine or stools, nosebleeding, easy bruising, black stools or bleeding that will not cease.
Yes
Heparin has been recalled by the FDA on two separate occasions. In December 2007, it was recalled due to contamination from Serratia marcescens bacteria which may cause serious illness or death. The following year, in March 2008, the drug made in China was again recalled because it was oversulphated.
- http://www.mayoclinic.com/health/drug-information/DR601931
- http://www.fda.gov/MedicalDevices/Safety/AlertsandNotices/ucm135345.htm
- http://www.fda.gov/Drugs/DrugSafety/PostmarketDrugSafetyInformationfor
PatientsandProviders/ucm112597.htm - http://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRes/resCollection_2.cfm?ID=69522&CREATE_DT=2008-05-09
-
July 30, 2010, 2:23 pm
-
July 30, 2010, 2:13 pm
-
July 29, 2010, 12:33 pm
-
July 28, 2010, 3:58 pm


