Onsolis
Generic Name:
Onsolis Description:
Onsolis, Fentora
Onsolis Side Effects:
The following side effects have been associated with Onsolis:
- Drowsiness
- Nausea
- Vomiting
- Urination problems
- Headache
- Vision changes
- Seizures
- Fainting
- Confusion
- Changes in heart rhythm
For more information, see our Onsolis side effects page.
Onsolis Uses:
Onsolis is a medication prescribed to patients who have developed a tolerance to their prescribed opiate medications used for cancer-related pain. These patients may experience “breakthrough pain”. Onsolis treats these sudden pain episodes by changing the way the brain and nervous system respond to pain.
Onsolis Interactions:
Patients should speak with their doctor about the use of any medications, vitamins or supplements before taking Onsolis.
Before beginning treatment with Onsolis, patients should consult their doctor if they are taking any of the following medications:
- Buprenorphine
- Butorphanol
- Nalbuphine
- Naloxone
- Nalmefene
- Pentazocine
- Phenytoin
- Rifabutin
- Rifampin
- Antibiotics
- Antifungal medication
- Aprepitant
- HIV or AIDS medication
- Verapamil
- MAO inhibitors
- Seizure medication
- Mental illness medication
- Nausea medication
- Pain medication
- Sedatives
- Sleeping pills
- Tranquilizers
- St. John’s Wort
- Ethanol
Patients with a history or current diagnosis of any of following conditions should consult their doctor before treatment with Onsolis:
- Seizures
- Diabetes
- Brain tumor
- Stoke
- Depression
- Hallucinations
- Head injury
- Lung disease
- Kidney disease
- Liver disease
- Mental illness
- Drug abuse or dependence
- Low blood pressure
- Alcohol abuse
- Heart problems
This is not a complete list of possible interactions. Patients should inform their doctor of all medicines they are taking to avoid any complications while taking Onsolis.
Onsolis Dosage Information:
Typical Dosage Recommendations
Onsolis dosages may vary among patients and conditions. Patients should take Onsolis exactly as prescribed by their doctor.
Onsolis is a disintegrating tablet intended to be placed above a rear molar at the onset of breakthrough pain symptoms. Biting, chewing, or sucking on an Onsolis tablet may cause you to swallow more of the medicine before it can be absorbed into your gums. This may give you less relief from your pain symptoms.
Leave the Onsolis tablet in place until it dissolves. This may take 14 to 25 minutes. If any part of the tablet remains after 30 minutes, swallow it with a glass of water.
If you still have breakthrough pain 30 minutes after your initial dose of Onsolis, your doctor may prescribe another dose to ease pain symptoms. After a second dose of Onsolis, you must wait another four hours before taking another dose of Onsolis for breakthrough pain symptoms.
Onsolis is packaged in a blister pack. Do not push a Onsolis tablet through the foil. Instead, peel back the foil on the blister pack and remove the tablet with dry hands.
Missing a Dose of Onsolis
It is unlikely you will miss a dose of Onsolis because it is usually taken as needed.
Onsolis Overdose
Patients who think they have overdosed on Onsolis should seek immediate medical attention. Symptoms of Onsolis overdose may include the following:
- Dizziness
- Drowsiness
- Confusion
- Breathing problems
Onsolis FDA Approval:
July 16, 2009
Onsolis Recall/Black Box Warning Information:
Onsolis carries a Black Box warning patients of serious adverse effects, including the risk of fatality while using Onsolis. Onsolis should only be prescribed to patients experiencing breakthrough cancer pain that are not receiving relief from other opioid medications. Onsolis also carries a warning for a high risk of misuse, abuse, or diversion.
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September 9, 2010, 3:38 pm
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September 8, 2010, 3:39 pm
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September 7, 2010, 9:59 am
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September 2, 2010, 12:51 pm
