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Orphenadrine Citrate

Generic Name: 

Orphenadrine citrate

Brand Names: 
Orphenadrine Citrate Description: 

Orphenadrine is a skeletal muscle relaxant that works to relieve the muscle pain and discomfort associated with various acute musculoskeletal conditions, including sprains, strains, aches, spasms, and other injuries. Used in conjunction with rest and physical therapy, orphenadrine citrate is a short-term treatment for the pain, stiffness, and range of motion limitations associated with muscle injuries.

Orphenadrine Citrate Side Effects: 

Serious side effects of orphenadrine citrate include:

  • Difficulty urinating or inability to urinate
  • Fainting
  • Fast or irregular heartbeat
  • Hallucinations
  • Skin rash

For more information, see our orphenadrine citrate side effects page.

Orphenadrine Citrate Uses: 

Orphenadrine citrate is used to temporarily relieve pain caused by various muscle conditions, including spasms, sprains, and strains.

Muscle spasms can occur after an injury, such as a strain or sprain, when the muscles or ligaments contract painfully. Often occurring in the back, muscle pain and spasms involve a rapid contraction of the muscles from irregular nerve impulses. Pain is an indication of the affected area’s sensitivity to further damage, and orphenadrine citrate used in combination with rest, ice, heat, and physical therapy can help to decrease the pain experienced from muscle spasms, as well as to help improve the recovery process.

Orphenadrine citrate is for short-term use only.

Orphenadrine Citrate Interactions: 

Tell your doctor about all prescription and non-prescription medications you may be taking along with orphenadrine citrate, including vitamins, nutritional supplements, and herbal products. The following drugs may interact with this medication:

  • Amatadine (Symadine, Symmetrel)
  • Antidepressants
  • Cold or allergy medications
  • Fluphenazine (Prolixin)
  • Haloperidol (Haldol)
  • Perphenazine (Trilafon)
  • Phenothiazines (chlorpromazine)
  • Potassium tablets
  • Prochlorperazine (Compazine)
  • Promethazine (Phenergan)
  • Propoxyphene (Darvon)
  • Sedatives or sleeping pills
  • Trifluoperazine (Stelazine)
Orphenadrine Citrate Dosage Information: 

Typical Dosage Recommendations

Orphenadrine citrate dosages may vary among patients. Your doctor will establish the size and frequency of your dosage according to your individual needs. It is important to follow the guidelines established by your doctor.

Orphenadrine citrate is administered as an injection given by a healthcare professional in a clinical setting. The injection is given into a vein (intravenously) or a muscle (intramuscularly) and may be repeated every 12 hours as needed.

Missing a Dose of Orphenadrine Citrate

If you miss a dose of orphenadrine citrate, take the missed dose as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose and wait to return to your regular dosing schedule.

Orphenadrine Citrate Overdose

Seek emergency medical attention if you think you have used too much of this medication.

Orphenadrine Citrate FDA Approval: 

July 16, 1981

Orphenadrine Citrate Recall/Black Box Warning Information: 

There is currently no black box warning on orphenadrine citrate.

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