Drug Alerts
Recently Added
Top 10 Pages

Pamelor

Generic Name: 
Brand Names: 

Aventyl, Pamelor

Pamelor Description: 

Pamelor is a tricyclic antidepressant that is used in the treatment of depression.

Pamelor Side Effects: 

Treatment with Pamelor may cause the following side effects:

  • Dry mouth
  • Nightmares
  • Jaundice
  • Decreased libido
  • Fatigue
  • Blurred vision
  • Constipation

For more information, visit our Pamelor side effects page.

Pamelor Uses: 

Pamelor is used to treat depression. Depression is a serious mental illness that can compromise quality of life and can also lead to suicidal thoughts and tendencies. Depression is a chronic illness that involves both the mind and the body and requires long-term treatment.

Symptoms of depression include:

  • Lack of interest in normal daily activities
  • Feeling sad, hopeless or worthless
  • Crying for no reason
  • Sleeping problems
  • Difficulty focusing, concentrating or making decisions
  • Weight gain or loss
  • Irritability or being easily annoyed
  • Restlessness
  • Feeling tired or weak
  • Loss of interest in sex
  • Thoughts of suicide or suicidal behavior
  • Unexplained physical problems

Pamelor is more likely to work for patients with endogenous depression, a biological imbalance of chemicals in the brain. This form of depression, rather than reactive depression (which is a response to an event or stress), is considered genetic.

Pamelor Interactions: 

The following medications are not recommended to be used in addition to Pamelor. Your doctor may decide to prescribe other medications:

  • Bepridil
  • Cisapride
  • Furazolidone
  • Grepafloxacin
  • Clorgyline
  • Isocarboxazid
  • Iproniazid
  • Levomethadyl
  • Linezolid
  • Mesoridazine
  • Metoclopramide
  • Moclobemide
  • Nialamide
  • Pimozide
  • Sparfloxacin
  • Terfenadine
  • Thioridazine
  • Toloxatone
  • MAO inhibitors
  • Antibiotics
  • Other antidepressants
  • Blood thinners
  • Thyroid medications
  • Sleeping pills
  • Muscle relaxants
  • Amphetamines
  • Lithium
  • Diabetes medications
  • Allergy or cold medications
  • High blood pressure medications
  • Anticonvulsants
  • Paroxetine
  • Phenprocoumon
  • S-Adenosylmethionine

Patients with a history or current diagnosis of any of the following conditions should consult their doctor before treatment with Pamelor:

  • Bipolar disorder
  • Schizophrenia
  • Glaucoma
  • Urinary retention
  • Enlarged prostate
  • Diabetes
  • Seizures
  • Overactive thyroid
  • Liver disease
  • Kidney disease
  • Heart disease
Pamelor Dosage Information: 

Typical Dosage Recommendations

Pamelor is available as a capsule and liquid. Dosage sizes range from 10 mg to 75 mg.

The initial adult dose for oral medications is 75 mg to 100 mg divided doses of 25 mg three or four times a day. Your doctor may increase your dose as needed. Teenagers and elderly adults may take 30 mg to 50 mg once a day or in divided doses.

Missing a Dose of Pamelor

If you miss a dose of Pamelor, take it as soon as possible. If it is time for your next dose, skip the missed dose and resume your dosing schedule. Do not double dose.

Pamelor Overdose

Seek emergency medical attention if you feel you have taken too much of this medication. Patients who overdose on Pamelor may exhibit the following symptoms:

  • Irregular heartbeat
  • Seizures
  • Fever
  • Vomiting
  • Stiff muscles
  • Coma
  • Fatigue
  • Irritability
  • Hallucinations
  • Dilated pupils
Pamelor FDA Approval: 

November 6, 1964

Pamelor Recall/Black Box Warning Information: 

Risk of Suicide/Depression

Pamelor contains a Black Box warning regarding an increase in suicidal thoughts and behavior when used in children, teenagers, and young adults with depression, specifically those under the age of 24. Patients who initiate treatment on antidepressants should be carefully monitored for worsening depression, suicidal tendencies or unusual changes in behavior.

follow us on twitter become a fan on facebook
Drug News & Alerts
Subscribe to RSS