Parnate
Generic Name:
Tranylcypromine Sulfate
Brand Names:
Parnate
Parnate Description:
Parnate is prescribed to adults for the treatment of certain types of depression.
The medication treats symptoms of depression by blocking the chemical monoamine oxidase, an enzyme that metabolizes certain chemicals (norepinephrine, serotonin and dopamine) in the brain. By preventing these chemicals from metabolizing, the levels of these neurotransmitters in the brain remain high, boosting a patient’s mood.
Parnate is typically prescribed when other anti-depressant medications have not proved successful. The medication is intended for use in patients who can be closely monitored.
Parnate Side Effects:
Parnate can cause serious side effects including:
- Anxiety
- Chest pain
- Dry mouth
- Depression
- Coma
- Fever
- Cough
- Irritability
- Nausea
- Seizures
- Shortness of breath
- Chills
- Jaundice
- Restlessness
For more information, see our Parnate side effects page.
Parnate Uses:
Adult patients with certain types of depression take Parnate to combat symptoms of the condition, often when other medications have proven unsuccessful.
Parnate Interactions:
Certain medications may interact with Parnate. Be sure to discuss the use of prescriptions, over-the-counter medications, vitamins and supplements with your doctor before beginning treatment with Parnate.
Parnate should not be used with the following medications:
- MAO inhibitors
- Dibenzazepine derivatives
- Sympathomimetics (including amphetamines)
- Certain central nervous system depressants (including narcotics and alcohol)
- Anti-hypertensive, diuretic, antihistaminic, sedative or anesthetic drugs
- Bupropion HCl
- Buspirone HCl
- Dextromethorphan
Additional medications interact with Parnate and should not be used with the medicine. Talk with your doctor about the use of Parnate with other medicines.
Patients taking Parnate should not consume:
- Cheese
- Foods with high levels of tyramine (often found in processed foods and soy)
- Excessive quantities of caffeine
Parnate Dosage Information:
Typical Dosage Recommendations
Take Parnate according to the dosing recommendations provided by your doctor.
Adults typically take Parnate tablets in a 30 mg dose, given in divided doses. A doctor may adjust the dosing, though patients usually do not take more than 60 mg of Parnate a day.
Missing a Dose of Parnate
If you miss a dose of Parnate, take the dose as soon as you remember. If it is nearly time for you next dose of the medication, skip the missed dose and take the next one to resume your normal dosing schedule.
Do not take double doses of Parnate.
Parnate Overdose
If a Parnate overdose occurs, seek emergency medical attention.
Parnate FDA Approval:
February 21, 1961
Parnate Recall/Black Box Warning Information:
A Black Box warning cautioning patients of the risk of suicidality in children adolescents and young adults with major depressive or other psychiatric disorders, especially in the first month of treatment with antidepressants, exists for Parnate.
Parnate is not approved for use in children.
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September 9, 2010, 3:38 pm
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September 8, 2010, 3:39 pm
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September 7, 2010, 9:59 am
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September 2, 2010, 12:51 pm
