Serevent
Salmeterol xinafoate
Serevent, Serevent Diskus
Serevent is a bronchodilator that is used to prevent asthma attacks. By relaxing the airway muscles, the medication is able to improve the patient's ability to breathe. Serevent is not intended to treat an asthma attack once it has already begun. In addition, because it is a long-lasting medication, it is generally recommended only to asthma sufferers who need to frequently use shorter-acting bronchodilators in order to obtain the desired results.
Serevent may also be used to treat chronic obstructive pulmonary disease (COPD) as well as for treatment of chronic bronchitis and emphysema when occurring separately.
Serevent is most commonly prescribed to individuals suffering from asthma, a condition characterized by the inflammation or tightening of the airway. Depending on the type of asthma, the airway may become filled with fluid. Some of the symptoms commonly associated with asthma include chest pain, coughing (particularly at night), pressure in the chest, shortness of breath, tightening of the chest, and wheezing.
When taking Serevent once in the morning and once in the evening, asthma sufferers who are over the age of 4 may experience relief from these symptoms. Because Serevent contains salmeterol, it may actually increase the patient's risk of asthma-related death. Therefore, it is only recommended for use with patients who are unable to control their condition with other shorter-acting asthma-controller medications.
Serevent may also be used in patients over the age of 4 who suffer from nocturnal asthma, exercise-induced bronchospasms, or obstructive airway disease, which may lead to bronchospasms and other breathing difficulties if left untreated.
Individuals who suffer from COPD may be able to treat bronchospasms with the help of Serevent. COPD refers to a group of lung diseases that are responsible for blocking airflow and making it difficult to breathe. The two conditions that are most commonly associated with COPD are emphysema and chronic bronchitis, both of which can be treated with Serevent.
COPD symptoms typically do not occur until long after lung damage has occurred. Symptoms associated with emphysema include shortness of breath (particularly when engaged in physical activity), tightness in the chest, and wheezing.
Symptoms associated with chronic bronchitis, which occurs mostly in smokers, include chronic cough that results in yellow-colored sputum, frequent respiratory infections, needing to clear your throat first thing in the morning, and shortness of breath.
Never use another form of salmeterol (such as Advair) or a similar inhaled bronchodilator such as formoterol or arformoterol (Foradil, Perforomist, Symbicort, or Brovana) while taking Serevent, unless your doctor has approved the combination.
Before using Serevent, tell your doctor if you are taking diuretics (water pills), antibiotics, antifungal medications, beta-blockers, antidepressants, HIV or AIDS medications, MAOI medications, decongestants, diet medicines, or caffeine.
Typical Dosage Recommendation:
To treat asthma and COPD, Serevent is prescribed as one inhalation used twice-daily (morning and evening). A typical dose of Serevent contains 50 mcg of salmeterol and 12.5 mg of lactose. If being used to treat exercise –induced asthma, use Serevent 30 minutes before exercising.
Missing a Dose:
If you miss a dose of Serevent, take one as soon as you remember, then wait 12 hours before using the medication again. If it is almost time for your next scheduled dose, skip the missed dose and wait until your next scheduled dose.
Overdosing:
Seek emergency medical attention if you think you have overdosed. Symptoms of overdose include muscle cramps, dry mouth, seizure, fainting, light-headedness, fast or irregular heartbeat, chest pain, tremors, or insomnia.
September 19, 1997
On November 18, 2005, the U.S. Food and Drug Administration (FDA) alerted health care professionals about the increased risk of worsening wheezing (bronchospasm) associated with long-acting bronchodilator medicines like Serevent in some patients.
A Black Box warning was added to Serevent Diskus to alert consumers that salmeterol and other long-acting medications may increase the risk of asthma-related death.
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July 30, 2010, 2:23 pm
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July 30, 2010, 2:13 pm
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July 29, 2010, 12:33 pm
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July 28, 2010, 3:58 pm


