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Actos Lawsuit

Multiple medical studies link the Type 2 diabetes medication Actos to the onset of bladder cancer. That life-threatening side effect, as well as heart failure, led thousands of people to seek compensation for damages caused by the drug.

Why People File Actos Lawsuits

Lawsuits filed by people injured by Actos list a number of counts against Takeda and Eli Lilly, including failure to warn about side effects and willfully concealing the safety concerns with the drug.

  • Failed to warn the public and health care providers that taking Actos for longer than 12 months may increase the risk of bladder cancer
  • Manufactured a defective product
  • Failed to properly test Actos
  • Concealed testing and research data from the public
  • Provided misleading data to the public
  • Manufactured an unsafe product
  • Knew the dangers of the product, but sold it anyway to maximize profits
  • Breached warranty by selling a drug that was not fit for use

Compensation for Actos Injuries

Filing a lawsuit can compensate people injured by the drug for emotional, physical and financial damages – a lawsuit can also send the company a message. There are several types of compensation that may be awarded if Takeda and Eli Lilly are found at fault.

Punitive Damages

Some people who file lawsuits do so to punish companies for misleading them and failing to warn the public. These damages are awarded to discourage drugmakers from similar conduct.

Medical Bills and Funeral Expenses

The cost of treatment can add up – including bills for checkups, surgery, medications, hospital bills, caregiving and funeral expenses. Lawsuits can help families cover these costs.

Lost Income

The inability to go to work because of medical problems – especially Actos bladder cancer – leads to lost income. Caregivers may also lose time from work as they care for a loved one.

Pain and Suffering

Dealing with Actos health problems, especially those that cause long-term damage, can also cause emotional suffering. Verdicts or settlements can help families to cope with these losses.

Loss of Consortium

Actos-related medical issues – specifically bladder cancer and the necessary surgeries and treatments -- can also damage intimate relationships. Spouses of Actos patients may be eligible to file this type of claim.

Serious Actos Complications

Actos can cause a number of serious side effects. One of the main reasons people file Actos lawsuits is to obtain compensation for medical expenses and other losses related to injuries caused by the drug. Two of the most serious potential side effects are bladder cancer and congestive heart failure.

Bladder Cancer from taking Actos

Bladder Cancer

Each year in the United States, about 70,000 people are diagnosed with bladder cancer. If caught before it spreads, the cancer can usually be treated. However, it has a high recurrence rate. Takeda does not acknowledge any links between Actos and bladder cancer.

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Congestive Heart Failure

The FDA considers the risk of congestive heart failure from Actos to be significant enough to require a black-box warning on the drug's label. Avandia, another drug in the same class, is also known to cause severe heart problems.

Learn More
Heart Failure After Taking Actos

Other Actos Complications

Did you take actos and develop bladder cancer or another serious complication? Fill out our Free Case Review form to find out what legal options you may have.

  • Heart Attacks
  • Liver Damage
  • Blindness
  • Bone Fractures
  • Kidney Damage

Actos and Bladder Cancer

Actos lawsuits claim Takeda Pharmaceuticals, the drug's manufacturer, and Eli Lilly, the drug's marketer, knew about the risk of bladder cancer and other side effects but did not warn the public. Since the drug was introduced in the 1990s, there has been a history of controversy surrounding the drug's link to bladder cancer and other side effects.

1999

Takeda and Eli Lilly launched Actos, a thiazolidinedione (TZD). Pre-approval studies showed tumors in rats given the drug. Its label said the relationship between the tumors in rats and possible tumors in humans is "unclear."

2005

Two clinical studies that were a part of Takeda's PROactive study revealed a higher percentage of bladder cancer in people taking Actos as opposed to another drug.

2006

Eli Lilly stops marketing Actos. The drug's label is changed to add the findings from a two-year study that showed bladder tumors in rats given a high dose of Actos.

2010

FDA begins reviewing data from 10 year Actos study

2011

French study finds increased bladder cancer risk in patients taking Actos. The drug is pulled off market in France, and Germany recommended not starting Actos in new patients.

2011

FDA releases safety announcement warning that using Actos for over a year "may be associated with an increased risk of bladder cancer."

2011

First Actos bladder cancer suits are filed.

Actos Lawsuits and Jury Verdicts

According to thousands of lawsuits, Takeda failed to adequately warn patients of the risk of bladder cancer associated with the medication. So far, more than 2,500 federal lawsuits are pending in the U.S. District Court for the Western District of Louisiana (MDL) No. 2299, and experts say that number could grow to 10,000. One man who sued Takeda told Bloomberg, "If somebody had told me I could get cancer from Actos, I never would have taken it. There were other products out there that could have helped treat my diabetes without putting me through all of this.” Other patients share a similar story.

Jack Cooper Awarded $6.5M

In 2013, a jury awarded Jack Cooper $6.5M in damages after he took Actos and was diagnosed with bladder cancer. Takeda was found guilty of failure to warn but convinced the judge a witness was unreliable and the verdict was overturned. Cooper's attorneys are appealing.

Darin Andrews

Louisiana resident Darin Andrews filed a lawsuit against Takeda in 2012 after being diagnosed with bladder cancer several months after he started taking Actos. His lawsuit states the drug was "inadequately tested, dangerous to human health and lacked proper warnings."

Edwene D. Person

Edwene Person's husband, James, was diagnosed with and died from bladder cancer after taking Actos. Her lawsuit states that James' injuries were a result of the defendants' "wrongful conduct, acts, omissions, [and] fraudulent misrepresentations."

Vanessa Blanco

Patient Advocate vblanco@drugwatch.com
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If you have questions about the dangerous side effects of Actos, bladder cancer or any other complications from the drug, our patient advocates are ready to chat with you.

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View Sources
  1. U.S. Food and Drug Administration (FDA). (2011, August 4). FDA Drug Safety Communication: Updated drug labels for pioglitazone-containing medicines. Retrieved from http://www.fda.gov/Drugs/DrugSafety/ucm266555.htm
  2. U.S. Food and Drug Administration (FDA). (2011, August 4). Letter to Jessie Y. Lee, Ph.D. Retrieved from http://www.accessdata.fda.gov/drugsatfda_docs/appletter/2011/021073Orig1s043s044-021842Orig1s014s015-022024Orig1s008s007-021925Orig1s010s011ltr.pdf
  3. Feeley, J. (2011, December 1). Takeda may face 10,000 U.S. suits over Actos cancer claims. Bloomberg. Retrieved from http://www.bloomberg.com/news/2011-12-01/takeda-may-face-10-000-u-s-suits-over-actos-cancer-claims.html
  4. Andrews v. Takeda Pharmaceuticals America et al.
  5. Person v. Takeda Pharmaceuticals America et al.
  6. Feeley, J. (2013, May 1). Takeda gets $6.5 Million Diabetes-Drug Verdict Thrown Out. Bloomberg. Retrieved from http://www.bloomberg.com/news/2013-05-01/takeda-gets-6-5-million-diabetes-drug-verdict-thrown-out.html
  7. Torsoli, Albertina. (2011, June 9). Takeda's Actos drug suspended in France on cancer risk study. Bloomberg. Retrieved from http://www.bloomberg.com/news/2011-06-09/takeda-s-actos-drug-suspended-in-france-on-cancer-risk-study-3-.html
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