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FDA Backs Xarelto Benefits Despite Recalled Clinical Trial Device

fda backs xarelto

After critics accused Johnson & Johnson and Bayer of hiding data in clinical trials for their blockbuster blood thinner Xarelto (rivaroxaban), the U.S. Food and Drug Administration said the drug [...]

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BMJ: J&J Hid Faulty Device from FDA in Xarelto Clinical Trial

J&J Hid Faulty Device from FDA in Xarelto Clinical Trial

Johnson & Johnson’s Janssen Pharmaceuticals knew about a faulty device and data in a Xarelto (rivaroxaban) regulatory trial that suggests they put participants at risk, The BMJ reports. Janssen withheld [...]

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PPI Heartburn Drugs Linked to Brain Problems, Fluid Build Up


Proton-pump inhibitors (PPIs) that treat acid reflux and heartburn may increase the risk for loss of brain function and fluid buildup in the abdomen, a study found. Nexium, Prilosec and [...]

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Study: PPI Acid Reflux Drugs Overused in People with GI Bleeds


More than half of patients with gastrointestinal (GI) bleeding receive acid reflux drugs called proton pump inhibitors (PPIs) even when guidelines discourage their use, according to a study. University of [...]

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FDA Strengthens Kidney Injury Warning on Invokana


The U.S. Food and Drug Administration released a safety communication informing the public of stronger kidney injury warning labels on SGLT2 inhibitors that treat Type 2 diabetes, including J&J’s Invokana/Invokamet [...]

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Drugs Like Prilosec & Nexium May Damage Arteries

Purple Nexium Pills

New research suggests that popular heartburn drugs called proton pump inhibitors (PPIs) such as Prevacid (lansoprazole), Prilosec (omeprazole) and Nexium (esomeprazole) may damage arteries leading to an increased risk of [...]

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