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Study: Knee Replacement Patients Likely to Gain Weight after Surgery

knee in bandages

It’s probably no surprise that overweight people are more likely than others to need total knee replacement (TKR) surgery, and they face more risks when they undergo the procedure. But a new study has found that any patient having TKR surgery is at risk of gaining weight afterward.

Scientists analyzed data from 1,000 such operations at the Mayo Clinic in Rochester, Minn., and found that 30 percent of patients gained 5 percent or more of their body weight in the five years following surgery. The results were published recently in the journal Arthritis Care & Research.

Activity Level and Age Can Play Role

Reuters reports that one possible explanation is that if people have spent years adapting to knee pain by being less active, they don’t necessarily change their habits after replacement surgery.

The weight gain also could be attributed to the age of the patients who typically have TKR procedures — men and women in their 50s and 60s. That age group tends to gain weight as they become more sedentary.

But the study authors say that weight gain can be avoided. “Future research should develop weight loss/maintenance interventions particularly for younger patients who have lost a substantial amount of weight prior to surgery, as they are most at risk for substantial post-surgical weight gain,” wrote study leader Daniel Riddle, a professor at Virginia Commonwealth University.

University of Delaware Study Finds Similar Results

The 2012 study isn’t the first to make the connection between weight gain and TKR surgery. A study sponsored by the National Institutes of Health and published Jan. 15, 2010, in the journal Osteoarthritis and Cartilage, found similar results.

Researchers at the University of Delaware reported that knee replacement patients usually lose weight after their procedures and then the pounds come back on. The average weight gain, they found, was 14 pounds over two years.

The study involved 106 people who had knee surgery and an age-matched control group of 31 individuals. Height, weight, leg strength and functional ability were measured before surgery and at a follow-up visit two years later.

The results? People who were overweight to begin with were heavier than the control group two years after surgery. Also, the weaker the patient before surgery, the more weight gained, said study co-author Joseph Zeni.

“For physical therapists and surgeons, the common thinking is that after a patient’s knee has been replaced, that patient will be more active,” said study co-author Lynn Snyder-Mackler. “But the practices and habits these patients developed to get around in the years prior to surgery are hard to break, and often they don’t take advantage of the functional gain once they get a new knee.”


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  1. Grens, K. (2012, December 9). Knee replacement linked to weight gain: study. Reuters. Retrieved from
  2. Riddle, D. et al. (2012, November 30). Clinically important body weight gain following knee arthroplasty: A five-year comparative cohort study. Arthritis Care & Research. Retrieved from
  3. Staff. (2010, February 16). Most Patients Gain Weight After Knee Replacement Surgery. Science Daily.
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