Pelvic Organ Prolapse

Pelvic organ prolapse is an uncomfortable condition that can occur in women after childbirth and menopause. It happens when weakened pelvic muscles allow the bladder, uterus or rectum to fall or sink into the vagina. Mild cases can improve on their own, but severe cases may require surgery.

Pelvic organ prolapse is a type of hernia, which is a condition that occurs when an organ bulges through the muscle or tissue that surrounds it.

Muscles, ligaments and fibers that attach to bone support the bladder, uterus and rectum. When the muscles weaken because of childbirth or other factors, the pelvic organs can fall into the vagina.

Nearly 3 percent of women in the United States suffer from POP, according to the Food and Drug Administration’s Office of Women’s Health. And surgeons perform roughly 200,000 surgeries to treat prolapse each year in the United States, according to an article by Dr. J. Eric Jelovsek in UpToDate.

POP is usually classified as asymptomatic or symptomatic. Asymptomatic means the organs drop but do not extend beyond the vaginal opening. Symptomatic means the organs or tissue extend beyond the vaginal opening.

The organ affected determines the type of prolapse.
Vaginal Vault Prolapse:
The top of the vagina falls
Uterine:
The uterus descends into the vagina
Cystocele:
The bladder protrudes into the vagina
Enterocele:
The small intestine protrudes into the vagina
Rectocele:
The rectum protrudes into the vagina

Patients experience pressure, pain or the sensation of something falling out of their vagina or rectum. In extreme cases, women may see or feel their pelvic organs bulge out of their body. When prolapse causes pain, patients should see a doctor.

Prolapse Causes and Prevention

Weakened or stretched pelvic muscles cause pelvic organ prolapse. Childbirth is the most common cause because it increases pressure on internal organs. That pressure can force the organs into the pelvis, leading to prolapse. Women who deliver larger babies are at an increased risk.

Studies indicate that:
  • One in three women who gave birth has prolapse
  • A woman who has two vaginal births is 8.4 times more likely to experience prolapse than a woman who hasn’t given birth vaginally
  • White women have a higher risk of prolapse than black, Hispanic or Asian women

Menopause, old age and other factors also contribute to weakened muscles. When women go through menopause, one side effect is a drop in their collagen levels. Collagen is a naturally occurring protein that helps connective tissue repair itself after stretching or tearing.

Other risk factors for pelvic organ prolapse include:
  • Multiple sclerosis
  • Spinal cord injury and paralysis
  • Muscular dystrophy
  • Chronic cough
  • Genetic weakness of connective tissue

Some causes of prolapse can’t be prevented. Injury to the pelvic floor from vaginal labor is unavoidable. Menopause is inevitable. And you can’t change family history that may put you at a higher risk for prolapse.

However, women can take steps to avoid certain factors that increase the risk of pelvic organ prolapse. These risk factors include smoking, obesity, heavy lifting, and intense activities, such as CrossFit.

Connective tissue in the pelvis can also weaken and cause prolapse when the uterus or cervix is removed during a hysterectomy. The risk of prolapse following a hysterectomy can be reduced if the doctor attaches the top of the vagina to ligaments in the pelvis during the procedure. This provides extra support to the pelvic organs.

Symptoms Develop Gradually As Muscles Weaken

Lower Back Pain Inflammation
Lower back pain is one of the symptoms of pelvic organ prolapse.

Symptoms of prolapse develop gradually as pelvic floor muscles weaken. Women will often feel pressure as the uterus, bladder or rectum press on the vaginal wall.

Pain during sexual intercourse, known as dyspareunia, is a common symptom of prolapse in women. Recurring urinary tract infections and pain during bowel movements or urination may also indicate prolapse.

Other symptoms of pelvic organ prolapse include:
  • Pulling and stretching sensation in the groin
  • Feeling bloated in the lower belly
  • Lower back pain
  • Spotting or bleeding
  • Constipation

Lifting objects, standing and jumping may worsen prolapse symptoms. Lying down can help alleviate symptoms.

People who experience multiple symptoms should see their primary doctor or OB-GYN. Doctors can run several tests to diagnose pelvic organ prolapse.

Diagnosing POP

People usually seek medical attention for prolapse when it causes pain and discomfort. A doctor can diagnose prolapse with a cotton swab test, a bladder function test or a pelvic-floor strength test. Primary care doctors or OB-GYNs may refer patients to a pelvic floor specialist called a urogynecologist for diagnosis and treatment.

During a cotton swab test, health care providers feed a small cotton applicator through a woman’s urethra. The patient must then strain or cough. This indicates the position of the bladder.

Bladder Function Test Materials
Materials necessary for a cotton swab test, bladder function test and pelvic-floor strength test – all used to diagnose pelvic organ prolapse.

A bladder function test uses a funnel to record a patient’s urine flow. If the bladder is under pressure from prolapse, the urine will flow at a certain rate. Doctors may insert a catheter through the urethra to fill the bladder with sterile liquid. The doctor will assess the bladder’s condition by measuring the pressure and volume of the bladder.

In a pelvic floor strength test, the patient uses his or her pelvic floor and sphincter muscles, and a health care provider measures muscle weakness.

If the prolapse is in an early stage, an MRI, X-ray, ultrasound, colonoscopy or cystoscopy can detect it. In cystoscopies and colonoscopies, doctors insert a small camera through the urethra or the rectum.

Stages of Pelvic Organ Prolapse

The Pelvic Organ Prolapse Quantification system provides a standardized method for classifying how far organs have prolapsed in women, according to a 2011 article in the Journal of Medicine and Life.

Five stages of prolapse:
  • Stage 0
    Organs are in their normal position
  • Stage 1
    An organ extends more than one centimeter above the hymen
  • Stage 2
    An organ is less than one centimeter from the hymen
  • Stage 3
    An organ extends more than one centimeter but less than two centimeters below the hymen
  • Stage 4
    The organ protrudes into the vagina

The POP-Q system measures six areas in the vagina to document how many centimeters the organs have fallen past the hymen. Doctors may use a long Q-tip as a ruler.

Centimeters above the hymen are negative points, which indicate less prolapse. Centimeters below the hymen are positive points, which signify more serious prolapse. Doctors total the points from each area to find the stage of the prolapse.

Treatment Options With and Without Vaginal Mesh

Pelvic organ prolapse can be a serious condition that lowers quality of life. Patients should talk to their doctors about all treatment options.

Depending on the stage of the prolapse, doctors may start by recommending treatment that slows the descent of the organs, such as Kegel exercises. Such conservative, non-surgical treatment options may provide relief from symptoms and help patients avoid surgery.

Doctors continue to monitor symptoms until prolapse causes pain or discomfort. When prolapse causes pain or discomfort, doctors may move to surgical methods.

If advanced prolapse is left untreated, organs can eventually bulge into the vagina or hang out of the body when standing or walking.

Overall, treatment options for pelvic organ prolapse are limited and long-term success rates are inconsistent. Some doctors refer to pelvic organ prolapse as a chronic disease because many women experience a recurrence of symptoms after treatment.

Conservative Treatments

Conservative treatment is the first line of therapy for treating POP, according to Jelovsek. Conservative treatment has the advantage of being safer, less expensive and less damaging to a patient’s body than surgery.

Kegel Exercises

Women can slow or prevent prolapse naturally by exercising their pelvic floor Kegel muscles. Kegel muscles control urination. Exercising them strengthens the pelvic area and supports the pelvic organs.

Low-Dose Estrogen Cream

Doctors often prescribe low-dose estrogen cream to strengthen pelvic connective tissue and slow the movement of prolapsed organs. Patients can apply estrogen creams vaginally once a day for the first two weeks of treatment and three times a week thereafter.

Pessary Insertion

Another conservative treatment involves inserting a device called a pessary into the vagina. This rubber ring provides support to organs. To lower the risk of side effects such as odor, vaginal discharge, infection, ulcers, irritation and bleeding, patients can apply estrogen cream with the device. Clean the pessary regularly and remove it before sexual intercourse.

Surgical Treatments

Many women may have POP but not suffer symptoms. There is no need for surgery in those cases. But women who are symptomatic — or asymptomatic with stage 3 or 4 prolapse — might be candidates for surgery.

Surgery can either be obliterative or reconstructive. Obliterative surgery narrows or closes off the vagina. It provides support for prolapsed organs, but women who undergo this procedure will no longer be able to have sex.

There are multiple types of reconstructive surgery. These procedures are intended to restore the pelvic floor and return organs to their original position. They can be done through an incision in the vagina or abdomen, or laparoscopically.

Sacrocolpopexy, which uses surgical mesh to treat vaginal vault prolapse and small intestine prolapse, and sacrohysteropexy, which uses surgical mesh to repair uterine prolapse, are done through an incision in the abdomen or with laparoscopy.

To repair prolapse through the vagina, doctors have traditionally turned to a surgical procedure known as colporrhaphy. During this procedure, a surgeon uses stitches and the patient’s own tissue to repair weakened muscles and create more pelvic floor support.

But because prolapse can return after colporrhaphy, gynecologists began using surgical mesh for transvaginal repair of POP in the 1990s. The FDA cleared the first surgical mesh product specifically for use in POP in 2002.

More medical device manufacturers, such as Johnson & Johnson, Boston Scientific Corp., C.R. Bard and American Medical Systems, began making transvaginal mesh kits to assist surgeons in the operation.

Medical device companies claimed that vaginal mesh was superior for treating prolapse, but the FDA has said there is no evidence to support those claims.

Because the FDA found that complications with transvaginal mesh are not rare, the agency asked for more safety data from manufacturers. Several companies simply stopped making POP mesh rather than doing the studies.

Lack of safety and efficacy data led the FDA to order manufacturers to stop selling mesh intended for transvaginal repair of POP in April 2019. There are currently no meshes for this use on the market in the United States.

Please seek the advice of a medical professional before making health care decisions.

Michelle Llamas, Senior Content Writer
Written By Michelle Llamas Senior Writer

Michelle Llamas has been writing articles and producing podcasts about drugs, medical devices and the FDA for seven years. She specializes in fluoroquinolone antibiotics and products that affect women’s health such as Essure birth control, transvaginal mesh and talcum powder. Michelle collaborates with experts, including board-certified doctors, patients and advocates, to provide trusted health information to the public. Some of her qualifications include:

  • American Medical Writers Association (AMWA) Engage Committee and Membership Committee member
  • Centers for Disease Control and Prevention (CDC) Health Literacy certificates
  • Original works published or cited in The Lancet, British Journal of Clinical Pharmacology and the Journal for Palliative Medicine
Edited By

10 Cited Research Articles

  1. Ashton-Miller, J. & DeLancey, J.O.L. (2009, July 6). On the Biomechanics of Vaginal Birth and Common Sequelae. Retrieved from  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2897058/
  2. Harvard Women’s Health Watch. (2014, May). What to Do About Pelvic Organ Prolapse. Retrieved from  https://www.health.harvard.edu/family-health/health-guide/what-to-do-about-pelvic-organ-prolapse
  3. Jelovesek, J.E. (2018, May 1). Pelvic organ prolapse in women: Choosing a primary surgical procedure. Retrieved from https://www.uptodate.com/contents/pelvic-organ-prolapse-in-women-choosing-a-primary-surgical-procedure
  4. Kudish, B.I. et al. (2011). Risk factors for prolapse development in white, black, and Hispanic women. Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/22453694/
  5. Memon, H.U. & Handa, V.L. (2013). Vaginal childbirth and pelvic floor disorders. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877300/
  6. National Association for Continence. (n.d.). Pelvic Organ Prolapse. Retrieved from  https://www.nafc.org/pelvic-organ-prolapse/
  7. Persu, C. et al. (2011). Pelvic Organ Prolapse Quantification System (POP–Q) – a new era in pelvic prolapse staging. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3056425/
  8. U.S. Food and Drug Administration. (2011, July). Urogynecologic Surgical Mesh: update on the Safety and Effectiveness of Transvaginal Placement for Pelvic Organ Prolapse. Retrieved from  https://www.fda.gov/media/81123/download
  9. U.S. Food and Drug Administration. (n.d.). A Fact Sheet from the Office of Women’s Health: Pelvic Organ Prolapse. Retrieved from https://www.womenshealth.gov/files/documents/fact-sheet-pelvic-organ-prolapse.pdf
  10. Voices for PFD. (2016). Pelvic Organ Prolapse. Retrieved from  https://www.voicesforpfd.org/assets/2/6/POP.pdf
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