Bladder Sling Complications

The most common type of bladder sling used to treat stress urinary incontinence is made of plastic mesh. Most women tolerate the procedure well, but mesh slings generally have a higher complication rate than slings made of tissue. Complications may occur during surgery or many years after.

A handful of countries have banned several transvaginal mesh products, including some types of slings, because of complications. Women receive these slings to treat stress urinary incontinence, or SUI. But mesh sling procedures may result in problems, such as bladder perforation, erosion of the mesh into the vagina and painful intercourse. Women who have suffered complications want the devices banned, and some have filed lawsuits against mesh makers.

“I was in terrible pain. My pelvic area was on fire,” Christy Hammond, a woman who received a sling for incontinence, wrote in an article published by Drugwatch. “Sex was out of the question because it hurt so bad. I was getting urinary tract infections (UTIs) on a regular basis.”

“I was in terrible pain. My pelvic area was on fire. Sex was out of the question because it hurt so bad. I was getting urinary tract infections (UTIs) on a regular basis.”

Christy Hammond, bladder sling recipient

Despite these complications, most doctors prefer mesh slings made of a plastic called polypropylene to treat SUI. The Food and Drug Administration and doctors agree bladder slings are less problematic than mesh for treating pelvic organ prolapse, or POP. In fact, the FDA reclassified surgical mesh for transvaginal repair of pelvic organ prolapse as a high-risk device in January 2016. And in April 2019, the agency stopped the sales of all mesh for POP repair in the United States.

The FDA’s halt on sales does not affect mesh for SUI. Women inured by bladder slings argue that polypropylene has the same risks regardless of the where doctors place the product.

Complication rates for bladder slings can vary depending on which study you are reading. This makes it difficult to get an accurate idea of how safe these devices are. Based on the studies it has reviewed, the FDA believes mesh slings for SUI are generally safe and effective.

“Mesh sling surgeries for SUI have been reported to be successful in approximately 70 to 80 percent of women at one year, based on women’s reports and physical exams,” the FDA said on its bladder sling page.

But the agency has found no advantage to using mesh slings.

“Similar effectiveness outcomes are reported following non-mesh SUI surgeries,” the agency said.

Minor and Long-Term Complications

Mesh slings have a higher complication rate than those made of native tissue. For example, synthetic mesh can cause infection, long-term pain and mesh erosion, a complication in which the mesh erodes surrounding tissue. None of these risks are present with slings made of tissue, according to the American College of Obstetrics and Gynecologists.

According to mesh manufacturer Boston Scientific, possible complications of mesh sling surgery include:
  • Local irritation at wound site
  • Infection
  • Urinary tract obstruction and urine retention
  • Vaginal extrusion
  • Erosion through the urethra
  • Scarring
  • Scar contracture
  • Inflammation
  • Fistula formation
  • Migration of the device
  • Pain
  • Recurrence of incontinence
  • Nerve damage
  • Swelling and redness at the wound site
  • Vaginal discharge
  • Fatigue
  • Shortness of breath
  • Bleeding

Minor complications, such as bleeding, short-term urinary retention and short-term pain after surgery, are typically easier to resolve. Long-term complications, such as vaginal extrusion, erosion, organ perforation and recurrent infections, can be more difficult to treat.

Women who experience long-term complications may need to undergo revision surgeries, which can be difficult. Infections, such as sepsis, can be life-threatening. Some of these problems can occur because of surgical technique.

Vaginal Extrusion and Erosion

One of the main concerns with bladder slings has been mesh extrusion or erosion. Extrusion and erosion both refer to mesh forcing its way into the vagina, bladder, urethra or other organ. In these cases, the mesh wears through the tissues.

According to a paper by Dr. Cristiano Mendes Gomes and colleagues, vaginal extrusion rates vary from 0 percent to 1.5 percent for retropubic slings, which are inserted through an incision in the vagina and positioned in a U shape around the urethra. The ends of retropubic slings are maneuvered between the bladder and pubic bone and brought out through incisions above the pubic bone.

For transobturator slings, the vaginal extrusion rates vary from 0 percent to 10.9 percent, according to the paper published in Internal Brazilian Journal of Urology. Known as TOT, this procedure avoids the space between the pubic bone and the bladder. Mesh is inserted through the vagina and the ends are brought out through incisions between the labia and the creases of the thighs.

Additionally, Gomes and colleagues found urethral erosion happened after less than 1 percent of sling surgeries.

Diagram of bladder sling placement
Expand
Mesh slings support the urethra to treat SUI, but mesh may erode into the vagina, bladder or other organs.

Dr. Charles Rardin, a urologist in Providence, Rhode Island, wrote in Ob.Gyn. News that long-term follow-up data indicates erosion occurs after 3 percent to 4 percent of sling placements as opposed to 1 percent as initially believed.

Some studies propose that the risk of erosion may be because of the surgical technique. But mesh that has more contact with the vaginal wall, such as the transobturator sling, may have a higher rate of vaginal erosion.

“Many of the reported cases of erosion occur several years, or longer, after surgery,” Rardin wrote. “It is hard to blame surgical technique for such delayed erosion.”

Know the Risks
Mesh slings can result in exposure and infection soon after surgery or many years later. This may lead to difficult mesh removal surgery, which can cause additional complications and may not fully resolve chronic pain or other side effects.
Source: The Royal Australian and New Zealand College of Obstetricians and Gynaecologists

Women who suffer this complication may have pain during intercourse, incontinence, urgency to urinate, urinary tract infections or obstructions.

Some women may not have any symptoms until the problem becomes more serious. This makes it more important for women who have had bladder sling surgery to follow up with their doctors regularly. Sometimes, erosion occurs just weeks after surgery.

Extrusion Case Study

In case studies published in the journal Urology, Dr. Andrew L. Siegel describes a 48-year-old woman who underwent an ObTape sling procedure. She complained of persistent yellow vaginal discharge, and her husband complained of pain during intercourse.

Extrusion Symptoms
One woman suffered vaginal extrusion three months after sling surgery. Her husband said he felt “teeth in her the vagina” during sexual intercourse.
Source: Vaginal Mesh Extrusion Associated with Use of Mentor Transobturator Sling by Dr. Andrew L. Siegel

“Three months postoperatively, she stated that her husband felt ‘teeth’ in her vagina during sexual intercourse,” Siegel wrote.

A pelvic exam revealed mesh extrusion.

In some cases, conservative management of erosion may be possible. For example, some surgeons may prescribe topical estrogen cream to help vaginal tissues heal.

But the woman experienced recurrent incontinence and needed to have the entire sling removed and a new sling placed.

Bladder and Bowel Perforation

Bladder and bowel perforation after mesh placement can result in serious infections and other problems. Perforation happens when mesh or surgical tools injure or cut through an organ.

Bladder perforation is the most commonly reported of these issues. It happens when surgeons puncture the bladder with a needle while placing mesh. But it can also happen when the edges of mesh cut the bladder. John Chang and Dominic Lee with St. George Hospital’s Department of Urology in Australia reported bladder perforation rates of up to 24 percent.

Risk Factors for Bowel Injury
In studies, older, thinner women who had prior pelvic surgery had a higher risk of bowel perforation.
Source: Fatal Injury of the Small Intestine during Retropubic Sling Placement by Peter Kasack and Branislav Kopcan

Most of the time, bladder perforation does not cause long-term injury, according to Rardin. Perforation typically occurs because of surgical technique. Surgeons can correct this if they diagnose the injury quickly. In some cases, patients may require a catheter to urinate while the injury heals.

Bowel perforations are far more serious injuries, and fortunately they are rare. These injuries are dangerous because bacteria can leak out of the bowel and cause life-threatening infections. Up until about 2008, the FDA received reports of at least nine bowel perforations. Six of those resulted in death, according to Chang and Lee.

Perforation Case Study

In a 2015 case report published in Case Reports in Obstetrics and Gynecology, authors Peter Kascak and Branislav Kopcan shared the story of a 66-year-old woman whose mesh pierced her small intestine after sling surgery. She had undergone surgery with an experienced specialist for sling placement, and there were no reported complications during surgery.

Initially, she did not suffer fever or other symptom of infection. However, she complained of nausea and vomiting the day after surgery. A CT scan showed inflammation of the abdominal wall, and doctors performed explorative surgery. They discovered the mesh sling had perforated her intestine and the contents of her bowel had leaked into the abdominal cavity. She went into septic shock and died three days after sling placement.

“Although the placement of midurethral sling is a minimally invasive surgery, good diagnostic skills, proper evaluation of indications, safe performance of the procedure, and thorough postsurgical monitoring are paramount for safe and effective outcome of the surgery,” authors wrote.

Kascak and Kopcan reported that intestinal injuries during sling placement were rare, and said that by 2004, the complication had occurred in about 35 out of 700,000 women. Seven of those patients died. Doctors were not aware of the cause until after death in five of those cases.

Complication Rates

The actual rates of mesh sling complications vary widely depending on the study, and several factors may influence reporting rates.

In one study published in Nature in 2017, Kim Keltie and colleagues followed 92,246 women who had had transvaginal mesh slings implanted for incontinence. The study found the complication rate within 30 days or five years of the mesh procedure was about 9.8 percent.

The most common complications after sling procedures are bladder perforation, voiding dysfunction, mesh erosion and post-operative pain, according to Rardin.

“Often times, complications can be significantly more impactful than the original urinary incontinence,” Rardin wrote. “It is important to take the complications of sling placement seriously. Let patients know that their symptoms matter, and that there are ways to manage complications.”

“Often times, complications can be significantly more impactful than the original urinary incontinence. It is important to take the complications of sling placement seriously.”

Source: Dr. Charles Rardin, Women & Infants’ Hospital, Division of Urogynecology

One of the difficult issues with bladder sling complications is that actual reported complication rates are inconsistent. Low complication rates may give women a false sense of security, while higher rates that occur under less experienced surgeons may scare women.

Dr. Elisabetta Costantini and colleagues published a review in the European Association of Urology journal that found most complications may be underreported. They offered several explanations for the scarcity of major complications in reports: Reports may understate complications; surgeons who have higher complications rates do not answer questionnaires; low-volume and high-volume surgeons experience differences; and surgeons who manage the complications may account for underreporting and over-reporting complication rates.

In addition, major and minor complications are challenging to diagnose and treat even for skilled surgeons, Costantini and colleagues said. These problems can occur during or after surgery. The rate of complications also depends on the technique and sling used in some cases.

Complications During or Shortly After Surgery

Intraoperative or perioperative complications occur during surgery or shortly after. In general, these are rarer. Complication rates range from less than 1 percent to 14 percent, according to Costantini and colleagues. Major complications such as vascular and nerve injuries and gut lesions occurred in less than 1 percent of women. Minor bladder injuries had rates from 0.5 to 14 percent. Significant blood loss occurred in about 2.7 percent to 3.3 percent of women.

Postoperative Complications

The majority of issues that women face with bladder slings occur after surgery. Sometimes, they may occur several years after. Gomes and colleagues reported some of the most recent postoperative complication rates gathered from several studies for retropubic and transobturator slings. Retropubic slings have a higher rate of complications in general, 4.3 percent to 75 percent.

2017 Average Rates of Postoperative Mesh Sling Complications
Complication Retropubic Sling Transobturator Sling
Bleeding 0.7 to 8 percent 0 to 2 percent
Bladder Injury 0.7 to 24 percent 0 to 15 percent
Urethral Injury 0.07 to 0.2 percent 0.1 to 2.5 percent
Urethral Erosion 0.03 to 0.8 percent 0.03 to 0.8 percent
Intestinal Injury 0.03 to 0.7 percent 0 percent
Vaginal Erosion 0 to 1.5 percent 0 to 10.9 percent
Urinary Tract Infection 7.4 to 13 percent 7.4 to 13 percent
Pain 4 percent 9.4 percent
Urgency urinating 0.2 to 25 percent 0 to 15.6 percent
Bladder obstruction 6 to 18.3 percent 3 to 11 percent
Urinary retention 4.0 to 19.5 percent 2.7 to 11 percent
Source: Update on Complications of Synthetic Suburethral Slings by Dr. Cristiano Mendes Gomes and colleagues

Complication Rates by Type of Sling

Before undergoing bladder sling surgery, women should ask their doctors about the technique they plan to use. Complication rates may vary depending on the type of mesh sling and technique.

A 2010 study of bladder sling procedures by Z. Chen and colleagues published in Urologia analyzed the outcomes of 187 women who received bladder slings to treat stress urinary incontinence. Authors found that transobturator vaginal tape inside-out (TVT-O) and transobturator vaginal tape out-inside (TOT) are simpler techniques with fewer complications compared to tension-free vaginal tape (TVT).

Women who used TVT had an average hospital stay of five days versus about two days for the TOT group.

The complication rate in the study was:
  • 15.6 percent for tension-free vaginal tape (TVT)
  • 9.20 percent for transobturator vaginal tape inside-out (TVT-O)
  • 8.90 percent for transobturator vaginal tape out-inside (TOT)

Complications from the procedures included discomfort with urinating, bleeding outside blood vessels and dysfunction of lower limbs. TVT was the only procedure associated with bladder perforation. Despite the complication rate, doctors found the slings safe.

“The three tension-free urethral suspension techniques have similar efficacy, all of them are safe and effective procedures for the treatment of female SUI,” authors wrote.

Please seek the advice of a medical professional before making health care decisions.

Michelle Llamas, Senior Content Writer
Written By Michelle Llamas Senior Writer

Michelle Llamas has been writing articles and producing podcasts about drugs, medical devices and the FDA for seven years. She specializes in fluoroquinolone antibiotics and products that affect women’s health such as Essure birth control, transvaginal mesh and talcum powder. Michelle collaborates with experts, including board-certified doctors, patients and advocates, to provide trusted health information to the public. Some of her qualifications include:

  • American Medical Writers Association (AMWA) Engage Committee and Membership Committee member
  • Centers for Disease Control and Prevention (CDC) Health Literacy certificates
  • Original works published or cited in The Lancet, British Journal of Clinical Pharmacology and the Journal for Palliative Medicine
Edited By

21 Cited Research Articles

  1. Albo, M.E. et al. (2007, May 24). Burch Colposuspension versus Fascial Sling to Reduce Urinary Stress Incontinence. Retrieved from  http://www.nejm.org/doi/full/10.1056/NEJMoa070416#t=article
  2. Boston Scientific. (n.d.). Mid-urethral Sling Procedure: Risks and Considerations. Retrieved from http://www.bostonscientific.com/content/gwc/en-US/patients/health-conditions/stress-urinary-incontinence/mid-urethral-sling-procedure/risks-and-considerations.html
  3. Chaliha, C. & Stanton, S. (2004). Risks and benefits of sling procedures. Retrieved from https://obgyn.onlinelibrary.wiley.com/doi/pdf/10.1576/toag.6.1.26.26971
  4. Chang, J. & Lee, D. (2017). Midurethral slings in the mesh litigation era. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522799/
  5. Chen, Z. et al. (2010). Comparison of three kinds of mid-urethral slings for surgical treatment of female stress urinary incontinence. Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/20890856
  6. Cleveland Clinic. (2014, October 30). Male Sling Procedure. Retrieved from  http://my.clevelandclinic.org/services/sling_procedure/hic_male_sling_procedure_for_urinary_incontinence.aspx
  7. Cochrane. (2017, July 30). Mid-urethral sling operations for stress urinary incontinence in women. Retrieved from https://www.cochrane.org/CD006375/INCONT_mid-urethral-sling-operations-stress-urinary-incontinence-women
  8. Costantini, E. et al. (2007). Managing Complications After Midurethral Sling for Stress Urinary Incontinence. Retrieved from http://eu-acme.org/europeanurology/upload_articles/Managing%20Complications%20after%20Midurethral%20Sling%20for%20Stress%20Urinary%20Incontinence.pdf
  9. Embury-Dennis, T. (2018, July 9). Government agrees to temporarily ban vaginal mesh implants for women with urinary incontinence. Retrieved from https://www.independent.co.uk/news/health/vaginal-mesh-implants-government-review-women-urinary-incontinence-health-risk-latest-a8439266.html
  10. Gerten, K.A. et al. (2008, June). Prolapse and Incontinence Surgery in the Older Woman. Retrieved from   https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3270581/
  11. Gomes, C.M. et al. (2017). Update on complications of synthetic suburethral slings. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678512/
  12. Kascak, P. & Kopcan, B. (2015, August 18). Fatal Injury of the Small Intestine during Retropubic Sling Placement. Retrieved from https://www.hindawi.com/journals/criog/2015/164545/
  13. Keltie, K. et al. (2017, September 20). Complications following vaginal mesh procedures for stress urinary incontinence: an 8 year study of 92,246 women. Retrieved from https://www.nature.com/articles/s41598-017-11821-w
  14. Nitti, V.W. (2012). Complications of midurethral slings and their management. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3481947/
  15. Rardin, C. (2015, March 24). Dos and don’ts for handling common sling complications. Retrieved from https://www.mdedge.com/obgyn/article/98216/surgery/dos-and-donts-handling-common-sling-complications
  16. Siegel, A.L. (2005). Vaginal Mesh Extrusion Associated With Use Of Mentor Transobturator Sling. Retrieved from http://andrewsiegelmd.com/files/MENTOR%20SLING%20EXTRUSION.pdf
  17. The American College of Obstetricians and Gynecologists. (n.d.). Surgery for Stress Urinary Incontinence. Retrieved from https://www.acog.org/Patients/FAQs/Surgery-for-Stress-Urinary-Incontinence
  18. The American College of Obstetrics and Gynecologists. (2017, July). Surgery for Stress Urinary Incontinence. Retrieved from https://www.acog.org/Patients/FAQs/Surgery-for-Stress-Urinary-Incontinence
  19. The Royal Australian and New Zealand College of Obstetricians and Gynaecologists. (2018). Position statement on midurethral slings. Retrieved from https://www.ranzcog.edu.au/getattachment/Statements-Guidelines/Gynaecology/Midurethral-Slings,-Position-Statement-%28C-Gyn-32%29/Position-statement-on-midurethral-slings-%28C-Gyn-32%29-Jan18.pdf?lang=en-AU&ext=.pdf
  20. U.S. Food and Drug Administration. (n.d.). Considerations about Surgical Mesh for SUI. Retrieved from https://www.fda.gov/MedicalDevices/ProductsandMedicalProcedures/ImplantsandProsthetics/UroGynSurgicalMesh/ucm345219.htm
  21. U.S. National Library of Medicine. (2015, January 21). Urinary incontinence – vaginal sling procedures. Retrieved from  https://medlineplus.gov/ency/article/007376.htm
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