Benzene is a common but toxic chemical. It is found in petroleum products and solvents. U.S. and international watchdogs recognize benzene as a cause of leukemia and other cancers. Studies show benzene exposure can increase the risk of certain cancers by as much as 40 percent. Research suggests even low-level benzene exposure can greatly increase the risk of leukemia.
Benzene is one of the most commonly used chemicals in the U.S. Several federal agencies list it as a known cause of cancer.
In 1987, the government significantly lowered the benzene exposure limit in the workplace. Medical research suggests the allowed amount in 2018 is still too high.
Benzene is a liquid compound. It is colorless, toxic and flammable. It has a sweet, gasoline-like aroma. But breathing it can cause serious complications including leukemia and nerve damage.
Oil companies add benzene to gasoline to boost octane. It gives gasoline much of its aroma. The chemical is also found in car exhaust.
Benzene is also used to make other chemicals. Manufacturers rely on benzene for products ranging from medicine to industrial solvents.
Most benzene exposure happens when people breathe in air containing benzene. People can also absorb it as a liquid through their skin. This can happen if people spill gasoline or solvents on themselves.
Benzene exposure usually happens in an industrial setting. But an act as simple as filling a gas tank can result in low-level exposure.
Chemical and petroleum industry workers may face long-term exposure. Mechanics and other people who work around engines, fuel or oil also face exposure risks.
The U.S. Occupational Safety and Health Administration (OSHA) sets strict limits on benzene in the workplace.
OSHA limits benzene exposure in the air to one part per million (ppm). That equals one ounce of benzene for every 350,000 cubic feet of air. Three hundred fifty thousand cubic feet is about the size of four Olympic swimming pools.
The level can go up to 5 ppm for no more than 15 minutes. Employers must provide protective equipment like respirators for people working around higher levels.
In the 1980s, the benzene exposure limit was 50 times greater. Research found the older, higher levels were more dangerous.
But a 2004 study suggested newer levels may still be too high for safety. That study examined Chinese shoe-factory workers. Their exposure was less than the U.S. benzene exposure limit. International researchers found the workers exhibited signs of increased leukemia risk. The study appeared in Science.
Studies link benzene exposure to several types of leukemia. Leukemia is a cancer of the blood-forming organs in the body. It can also cause other blood-related complications. Benzene exposure can damage skin, eyes and affect the nervous system.
Chronic myeloid leukemia (CML) is among the most serious complications of benzene exposure. It starts in bone marrow. When CML grows, it expands into the blood. From there, it can spread through the body. It may attack the spleen.
CML is slow growing. But in some cases it can turn into a much faster growing leukemia. Once that happens, it becomes more difficult to treat.
Leukemia is benzene’s most serious, long-term health risk. Studies have found even low benzene exposure can increase leukemia risk.
A 2015 benzene study looked at leukemia risks from low exposure. Researchers examined medical histories of 25,000 Norwegian oil rig workers. All had worked on off-shore rigs for at least 20 days. The researchers found even with low exposure levels, the leukemia risk was high. They published their work in the British Journal of Cancer.
The researchers said their findings were in line with previous low-exposure benzene studies. A 2007 study in Cancer Causes & Control found a three-fold increased risk for acute myeloid leukemia (AML). A 2003 study in Epidemiology found a seven-fold increase in acute non-lymphocytic leukemia risk.
The 2015 study also found that the risk was even greater before 1980. It was about that time that governments set new benzene exposure limits. U.S. and international agencies have long known of benzene’s link to cancer.
A 2012 study found benzene exposure can increase the risk of chronic myeloid leukemia (CML) by 23 percent. That study appeared in the American Journal of Industrial Medicine.
In 2010, researchers analyzed 15 benzene exposure studies. They estimated there was a 40 percent average risk of leukemia from benzene exposure. They also linked higher exposure to higher risk of leukemia. They found the risk more than doubled for people with the greatest benzene exposure. The study appeared in the journal Environmental Health.
People who work around benzene should wear safety gear to limit exposure. Proper clothing can prevent skin contact. Protective eyewear can prevent benzene from getting in the eyes. People should wear respirators if working around higher levels of benzene.
People filling their gas tanks should avoid breathing in gasoline fumes. They should use pumps with vapor capture devices to reduce exposure risks.
Signs and symptoms of benzene exposure range from simple irritation to serious medical conditions. They can happen within seconds of exposure. Some symptoms can take weeks to show up.
Immediate treatment includes moving into fresh air. Those exposed to Benzene should wash their skin or flush their eyes after benzene contact. People should quickly remove any clothing that has benzene on it. They should cut off any contaminated clothing rather than pulling it over their head.
People should speak to a doctor if they think they experienced long-term benzene exposure. Doctors use blood, breath or urine tests to detect benzene exposure. While tests can measure benzene exposure, they cannot predict long-term health effects.
Workers began filing lawsuits over benzene exposure in the 1990s. This followed OSHA’s decision to lower the benzene exposure limit. It also came as other institutions declared benzene a known cause of cancer.
Court documents show that large oil and chemical companies knew about benzene’s risks since the 1940s. Workers who developed leukemia after benzene exposure claim the companies were negligent. Their lawsuits claim the companies could have done more to protect them.
Please seek the advice of a medical professional before making health care decisions.
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