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Nexium, Prilosec & Other PPI Lawsuits

Nexium lawsuits and Prilosec lawsuits account for most of the 4,200 proton pump inhibitor lawsuits filed in federal court. Recent studies show proton pump inhibitors like Prilosec, Nexium, Prevacid and Protonix increase patients’ risk of serious kidney injuries. Prilosec and Nexium lawsuits blame PPI manufacturers for failure to warn about the risk of acute interstitial nephritis, chronic kidney disease, renal/kidney failure or acute kidney injury.

Suffering from serious side effects after taking a PPI?

If you took a Proton Pump Inhibitor (PPI) like Nexium or Prilosec and suffered kidney damage or injuries, you may be entitled to compensation.

Nexium, Prevacid & Prilosec
PPI Lawsuit Facts
  1. Injuries Kidney disease, kidney injury, kidney failure, acute interstitial nephritis
  2. Manufacturers/Defendants AstraZeneca; Pfizer; Proctor & Gamble; Takeda Pharmaceuticals
  3. Top Settlement $55 million settlement
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Drugwatch content is legally reviewed for accuracy and quality.

Examples of trusted legal reviewers include qualified mass torts lawyers and certified paralegals.

Drugwatch writers gather lawsuit information by studying court records, watching lawsuit proceedings and speaking with experienced attorneys.

*UPDATE: The number of proton pump inhibitor lawsuits grew by 800 percent in the first four months of 2018. Drugwatch’s legal partners are currently taking Nexium, Prilosec and other PPI lawsuit cases.

As of August 2018, there were 4,725 proton pump inhibitor lawsuits in federal court. A federal panel combined PPI lawsuits into a multidistrict litigation (MDL) in August 2017. MDLs allow similar cases to move more efficiently through the legal process.

The MDL judge has scheduled the first bellwether trial for Sept. 21, 2020. Bellwether trials are “test cases” for MDLs. They can measure jury responses to arguments from both sides. Sometimes they can shape settlements.

Nexium and Prilosec lawsuits account for most of the cases. The MDL also includes Prevacid lawsuits and Protonix lawsuits. PPI lawsuits claim the drugs used to control stomach acid caused serious kidney problems.

Proton pump inhibitor lawsuits are in the very early stages. There have been no major verdicts or settlements in PPI kidney lawsuits.

Timeline of PPI Lawsuits
  • MAY 2016
    People filed the first Nexium kidney damage lawsuits against AstraZeneca.
  • FEBRUARY 2017
    The federal MDL panel denied a motion to combine 39 PPI lawsuits into an MDL. The lawsuits were against several different PPI manufacturers and named different drugs.
  • JULY 2017
    The federal panel reconsidered requests to create an MDL.
  • AUGUST 2017
    The MDL panel centralized 161 PPI cases into one action in a New Jersey federal court. It included lawsuits against five PPI manufacturers.
  • August 2018
    The total number of PPI lawsuits in the MDL grew to 4,725.
  • SEPTEMBER 2020
    The first bellwether trial is scheduled to start.

Attorneys expect the MDL could include thousands more lawsuits. PPI lawyers are taking new cases.

Why People File PPI Lawsuits

Lawsuits claim Prilosec, Nexium and other PPIs caused kidney-related complications. Lawsuits claim people “suffered and continue to suffer” from PPI side effects.

People who developed kidney complications filed many of the lawsuits. But people who lost a loved one to fatal kidney complications also filed PPI lawsuits.

People claim in lawsuits that PPIs caused:
  • Kidney disease
  • Kidney injury
  • Kidney failure
  • Acute interstitial nephritis (AIN)

PPI lawyers argue many people may have been able to avoid these injuries by using alternatives to PPIs.

Are you suffering kidney complications from a Proton Pump Inhibitor? Get a Free Case Review
Replay Video
Rebecca Montrone discusses the problems associated with proton pump inhibitors, many of which have led to legal action.

Accusations Against Makers of Nexium, Prilosec and Other PPIs

Proton pump inhibitor lawsuits claim manufacturers knew of kidney risks for years. But they never warned people of the dangers.

Accusations in PPI Lawsuits
  • Negligence
  • Misbranding
  • Deceptive advertising
  • Negligent misrepresentation
  • Fraud
  • Failure to warn of PPI side effects
  • Accepting kickbacks
  • Designing, manufacturing and selling defective products

PPI lawsuits allege that because manufacturers didn’t warn of the risks, doctors did not know to inform their patients. And patients did not know what questions to ask about PPIs.

PPI Brands and Manufacturers Facing Lawsuits

The proton pump inhibitor MDL involves four manufacturers. It includes five specific brands of heartburn medicines.

Drug Name (Generic Name) Manufacturer
Nexium (esomeprazole) AstraZeneca
Prilosec (omeprazole) AstraZeneca
Prilosec OTC (omeprazole) Proctor & Gamble
Prevacid (lansoprazole) Takeda Pharmaceuticals
Protonix (pantoprazole) Pfizer

How to File a Prilosec, Nexium or Other PPI Lawsuit

Are you suffering from kidney problems after taking a PPI? Get a Free Case Review

People who took PPIs and suffered kidney damage may be able to sue the manufacturers. Patients can enlist the help of products liability lawyers who specialize in medical cases.

Prilosec or Nexium cases can involve complex legal and medical issues. A PPI lawyer has experience in these kinds of cases.

Most PPI attorneys offer free consultations. They also do not charge fees unless they win the case. People should ask lawyers about all fees before talking with them.

Verdicts and Settlements Against PPI Manufacturers

The current proton pump inhibitor MDL is still in the very early stages. There have been no major verdicts or settlements yet.

But past PPI lawsuits for other causes included a $784 million settlement. Most settlements so far have resulted from lawsuits the government filed. These targeted PPI manufacturers’ business practices.

Prilosec and Prilosec OTC Lawsuits

kidney damage illustration
Prilosec lawsuits claim the medicine caused kidney damage

Most of the drugs named in the PPI multidistrict litigation are prescription versions. But lawsuits name both prescription and over-the counter versions of Prilosec in lawsuits.

Both are forms of omeprazole. Prilosec OTC is one of the more popular over-the-counter PPIs available.

Prilosec lawsuits claim the medicine caused kidney damage or injury. They allege manufacturer AstraZeneca knew of kidney risks as early as 2004. But the company never warned patients about it for 10 years.

There have been no trials or settlements in current Prilosec lawsuits.

“Ruffenach et al., published the first case report of AIN due to omeprazole (Prilosec) in 1992. Since, then reports have emanated from many national adverse drug registries.”

Source: Indian Journal of Nephrology

Nexium Lawsuits and $7.9 Million Settlement

Current Nexium lawsuits claim the medicine caused serious kidney problems. None of those cases have gone to trial yet. There have been no verdicts or large Nexium settlements to date.

Previous Nexium lawsuits claimed the medicine contributed to bone fractures. The federal MDL panel combined dozens of Nexium bone fracture lawsuits in 2012. But a federal judge threw out the MDL two years later.

Timeline of Nexium Bone Fracture Lawsuits
  • 2011
    First Nexium lawsuit filed against AstraZeneca. It claimed Nexium led to a woman’s bone fractures.
  • 2012
    A federal court panel combined 47 Nexium lawsuits. It centralized the multidistrict litigation in a California federal court.
  • 2012
    The MDL panel identified more than 1,000 Nexium lawsuits against AstraZeneca.
  • 2014
    The MDL judge closed the MDL in favor of AstraZeneca.

In 2015, AstraZeneca agreed to a $7.9 million Nexium settlement with the U.S. government. The Justice Department accused the company of a kickback scheme. The government claimed AstraZeneca worked with another company to boost Nexium sales.

Nexium Sales
Nexium is the all-time third best-selling medicine in the U.S. It had $72.5 billion in sales between 1992 and 2017.

Prevacid Lawsuits and Settlements

The FDA approved Prevacid in May 1995.

Active Prevacid lawsuits blame the heartburn medicine for serious kidney issues.

Those lawsuits are part of the PPI multidistrict litigation. There are no Prevacid settlements or verdicts for kidney problems yet.

Previous Prevacid lawsuits claimed it caused bone fractures. In 2014, Takeda Pharmaceuticals reached a Prevacid settlement in a bone fracture lawsuit.

The amount of the settlement remains undisclosed.

Protonix Lawsuits and $784 Million Settlement

Current Protonix lawsuits are part of the PPI kidney damage MDL. There have been no large verdicts or settlements in any of those cases yet.

But Pfizer has agreed to two large Protonix settlements with the U.S. government. In 2016, Pfizer agreed to a $784 million Protonix settlement. The government had accused Pfizer’s Wyeth unit of overcharging Medicaid for Protonix.

In 2012, Pfizer agreed to a $55 million Protonix settlement. The government claimed the company marketed Protonix for unapproved uses.

Nexium and Prilosec Class Action Lawsuit

In 2015, AstraZeneca agreed to settle a Nexium and Prilosec class action lawsuit. The company paid $20 million to consumers.

The Prilosec and Nexium class action targeted marketing practices. It claimed AstraZeneca spent $260 million on a misleading advertising campaign. The goal was to mislead consumers into buying more expensive medicine.

The class action accused AstraZeneca of attempting to “evergreen” the medicines. That is, the company tried to keep market share as a patent expired.

AstraZeneca’s patent on Prilosec was about to expire. The lawsuit claimed the company pushed Nexium to replace it. The two drugs were almost chemically identical. But Nexium was far more expensive than Prilosec.

Please seek the advice of a medical professional before making health care decisions.

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35 Cited Research Articles

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